Actualización en plasma rico en plaquetas

Autores/as

  • Silvia E. Castro Piedra Instituto Tecnológico de Costa Rica
  • Karla A. Arias Varela Centro de Excelencia de Investigación de Terapias de Avanzada

DOI:

https://doi.org/10.51481/amc.v61i4.1044

Palabras clave:

plasma rico en plaquetas, péptidos y proteínas de señalización intercelular, dermatología, regeneración, sistema músculo-esquelético

Resumen

El plasma rico en plaquetas es un producto derivado de la sangre, rico en péptidos y proteínas de señalización intercelular, así como citoquinas capaces de intervenir en cada una de las etapas de la regeneración de varios tejidos. Principalmente, se le han atribuido efectos antiinflamatorios en diferentes lesiones, así como otros efectos biológicos sobre las células y tejidos. A la fecha, no existe un protocolo estándar de producción o preparación, tampoco se ha descrito una dosis específica; la forma de aplicación es muy variable y depende de la condición por tratar. A pesar de ello, se han visto efectos positivos en campos como: odontología, ortopedia, dermatología, medicina reconstructiva, oftalmología, medicina deportiva, medicina vascular, entre otros. Su regulación es muy diversa a nivel internacional. Aunque hay expectativas con el tratamiento de plasma rico en plaquetas, no hay suficientes ensayos clínicos robustos que brinden un alto nivel de evidencia para validarlo como un tratamiento de rutina frente a determinada condición clínica. Además, no se pueden comparar fácilmente los resultados de diferentes investigaciones, por la variabilidad en el método de preparación y por la falta de homogeneidad en las lesiones tratadas, entre otros factores. Es por lo anterior que resulta necesario desarrollar más investigaciones serias que conlleven al establecimiento de un protocolo estandarizado, así como demostrar la efectividad de este nuevo tratamiento, de forma que se culmine con la implementación de nuevas terapias validadas y autorizadas para garantizar una mejoría real a los pacientes.

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Citas

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Publicado

2019-10-29 — Actualizado el 2019-10-29

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Cómo citar

Piedra, S. E. C., & Varela, K. A. A. (2019). Actualización en plasma rico en plaquetas. Acta Médica Costarricense, 61(4), 142–151. https://doi.org/10.51481/amc.v61i4.1044